I've never known any method of changing the MAC address on the Pineapple, although if dark_pyrro says to use macchanger, then I don't doubt that it works. Er, the MACs could also be editable under the AP settings. I don't remember. Bear in mind that if you leave your Pineapple at home, this is irrelevant.
Like dark_pyrro also said, the IP address isn't something to usually worry about. There are tools that can spoof the source IP as mentioned, but it's normally used for DoS or Nmap Idle scans. Static IP addressing is what you'll want if you're needing to get responses. What you may really want is ARP spoofing.